Lorazepam: Uses, Dosage & Side Effects

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Lorazepam is a drug belongs to benzodiazepine. It is mainly used treat seizures, and it is also called as an anti-epileptic drug.  It is also used to treat anxiety, panic disorders (including agoraphobia) in adults.

Information about Lorazepam:

It is not to be used in the patients who were having glaucoma or severe liver disorders, seek medical emergency if you have worsening symptoms such as depression, unusual changes in the behavior or suicidal thoughts or hurting yourself.

Do not consume alcohol because it can aggravate the side effects. Lorazepam is habit-forming, so it never shares this medicine with others, keep at the place, children are not able to take.

Dosage pattern of Lorazepam:

Adult dose:

anxiety:

It is about 3mg to be taken orally per day divided into 2-3 doses, it may be increased to 0.5mg more until the symptoms of the seizures were diminished.

Use: used in symptoms of anxiety

Anesthesia:

IM: it is about 0.05mg/kg , maximum dose is 4mg

IV: it is about 2mg total or 0.044

Pediatric dose:

It is administered orally, to minimize the drowsiness. The initial dose is based on the weight of the child.it is about 0.01-0.03mg/kg per day, given in two to three divided doses. If the doses are not equally divided, the larger dose can be given.

Geriatric dose:

There are no clinical trial experiments with lorazepam in seizure disorder, in general, elderly patients should have start low doses, but in the close observance.

Panic disorder:

Initial dose is about 2.5mg orally for every 2 times a day,

Maintenance dose: it is about 1mg to be taken orally per day

Maximum dose: it is about 4mg orally per day

Use: treatment of panic disorder

Pediatric dose

Seizures prophylaxis

10yrs of age 30kg body weight:

It is about 0.01mg /kg per day to 0.05mg/kg per day orally administered in 2-3 divided doses.

Use: treatment of petit mal epilepsy

Lorazepam overdose:

The symptoms of overdose are

  • Extreme drowsiness
  • Muscle weakness
  • Confusion
  • Fainting
  • coma

Lorazepam side effects:

Severity: major

More common:

  • headache
  • cough
  • chills
  • difficulty in breathing
  • fever
  • irritability
  • lack of appetite
  • loss of voice
  • runny nose
  • sneezing
  • Tiredness
  • Trouble with concentration
  • Insomnia

Less common:

  • Bladder pain
  • Bloody urine
  • Joint pains
  • diarrhea
  • loss of appetite
  • Lower back pain
  • Nausea
  • Nervousness
  • Shivering
  • Slurred speech
  • Sore throat
  • Vomiting
  • Trouble with speaking

Severity: major

Less common

  • Decreased libido
  • Heavy bleeding
  • Loss of sexual ability
  • Voice changes

Rare:

  • Joint pain
  • Blurred vision
  • Difficulty in moving
  • Double vision
  • Hair loss
  • Heartburn
  • Indigestion
  • Menstrual irregularities
  • Itching
  • Red, sore eyes
  • Thirst

Lorazepam: brand names, price list.

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