Metformin: Uses, Dosage & Side Effects

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Metformin is an oral diabetic drug. And it helps by controlling the sugar level from high to normal levels. It works by the regulating the insulin levels in the body after eating.

It is commonly used to treat the people with type 2 diabetes and is also given along with the other diabetic medications. But it is not recommended for treating with the type 1 diabetes.

Information about Metformin:

This medicine is not used by the patients suffering from kidney diseases. It is also not to be used if the patient having diabetic ketoacidosis. You should not take the medicines if you are allergic to the sitagliptin. This medicine can cause the serious condition called lactic acidosis (condition where lowers the pH levels).

  • Kidney diseases
  • Pancreatitis
  • Higher triglycerides
  • Alcoholism
  • Gallstones

It is cautioned that pregnant ladies and lactating mothers should take this medicine on medical advice only.

This medicine should be used as exactly how the doctor has prescribed and it is must for the patient to follow the directions written on the prescription label. It should not be used in small or large doses and also not for longer duration than prescribed. This medicine should be taken for only 4-8 weeks and if any extension is required then consult your doctor.

Do not crush or chew the tablets or capsules. Do not swallow the tablets or capsules rather consume it with a full glass of water.

Dosage pattern of the Metformin:

For Adult dose

Immediate release

Initial dose: 500 mg to be taken orally twice in a day or 850 mg to be taken orally twice in a day

Maintenance dose: 2000 mg daily, once in a day.

Maximum dose: 2550 mg daily once in a day.

Extended release

Initial dose: is about 500-100 mg orally once in a day.

Maintenance dose: is about 2000 mg daily once in a day.

Maximum dose: it is about 2500mg daily once in a day

The recommended dose of Januvia is 100 mg once in a day. This medicine can be taken with or without food.

For Paediatric dose:

If the children age is above 10 yrs

Immediate release

Initial dose: 500 mg is to be given orally twice a day or 850 mg to be taken orally twice in a day.

Maintenance dose: 2000 mg daily once in a day.

Maximum dose: 2550 mg daily once in a day.

Renal insufficiency:

For patients with mild renal insufficiency, no dose adjustment is required.

For the patients with moderate renal insufficiency, the dose is about 50 mg can be taken once in a day.

For the patients with severe renal insufficiency, the dose is about 25 mg can be taken once in a day.

Combination with insulin:

When this medicine is used in combination with the insulin derivatives such as sulfonylureas (even after using in lower doses also) can cause hyperglycemia.

Metformin Side effects:

If any on of the following side effects are seen or experienced by the patients then immediately consult your doctor.

Severity: major

  • Confusion
  • Anxiety
  • Cold sweats
  • Chills
  • Blurred vision
  • Depression
  • Dizziness
  • Nausea
  • Nervousness
  • Nightmares
  • Seizures
  • Slurred speech

Severity: minor

  • Loss of voice
  • Fever
  • Muscle ache
  • Sneezing
  • Sore throat
  • Cough
  • Breathing difficulty
  • Runny nose
  • Diarrhea
  • Stomach pain
  • Loss of voice

Metformin: brand names, price list.

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