Metformin: Uses, Dosage & Side Effects

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Metformin is an oral diabetic drug. And it helps to control the sugar level normal. It mainly works by the regulating the insulin levels in the body after eating.

It mainly used to treat the people with type 2 diabetes; it is given along other diabetic medications. But it is not used for the treating the type 1 diabetes.

Information about Metformin:

The patients with kidney disease are not to be used. It is not to be used if the patient having diabetic ketoacidosis. You should not the medicines if you’re allergic to the sitagliptin. This medicine can cause the serious condition called lactic acidosis. Make sure this medication is safe for you. It is not used if you have following:

  • Kidney diseases
  • Pancreatitis
  • Higher triglycerides
  • Alcoholism
  • Gallstones

It is not expected to harm the unborn baby, but tell the doctor if you’re pregnant or going to be pregnant. It can be used as the exactly how the doctor has prescribed, directions written on the prescription label should be followed by the patient. It is not to be used in small or large doses and also no longer than prescribed.

It is not approved for the usage of anyone younger than the 18yrs of age.

Dosage pattern of the Metformin:

Adult dose

Immediate release

Initial dose: 500mg to be taken orally twice a day or 850mg to be taken orally twice a day

Maintenance dose: 2000mg daily

Maximum dose: 2550mg daily

Extended release

Initial dose: it is about 500-100mg orally once in a day

Maintenance dose: it is about 2000mg daily

Maximum dose: it is about 2500mg daily

The recommended dose of Januvia is 100mg once a day. It can be taken with or without food.

Pediatric dose:

10yrs

Immediate release

Initial dose: 500mg to be taken orally twice a day or 850mg to be taken orally twice a day

Maintenance dose: 2000mg daily

Maximum dose: 2550mg daily

Renal insufficiency:

For patients with mild renal insufficiency, no dose adjustment is needed

For the patients with moderate renal insufficiency, the dose of Januvia is about 50mg once in a day.

For the patients with severe renal insufficiency, the dose of Januvia is about 25mg to be taken for a day.

Combination with insulin:

When Januvia is used in combination with the insulin derivatives such as sulfonylureas. Or may in lower doses it can cause hyperglycemia.

Metformin Side effects:

Severity: major

  • Confusion
  • Anxiety
  • Cold sweats
  • Chills
  • Blurred vision
  • Depression
  • Dizziness
  • Nausea
  • Nervousness
  • Nightmares
  • Seizures
  • Slurred speech

Severity: minor

  • Loss of voice
  • Fever
  • Muscle ache
  • Sneezing
  • Sore throat
  • Cough
  • Breathing difficulty
  • Runny nose
  • Diarrhea
  • Stomach pain
  • Loss of voice

Metformin: brand names, price list.

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