Ondansetron (Zofran) : Uses, Dosage & Side Effects

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Ondansetron (Zofran) works majorly on the chemicals in the body that can trigger nausea and vomiting. Thereby controlling the conditions.

Ondansetron is generally used to prevent nausea and vomiting which is caused by the surgery and by the cancer medication.

Information about Ondansetron:

It should not be used if the patient using apomorphine and also not to be used in case of allergic to this medication. This medicine may even interact with the medicines such as dolasetron, granisetron, palonosetron and etc. Inform your doctor if you are having liver disease at present or as a history.

Dosage pattern of Ondansetron:

Adult dose:

For Nausea and vomiting induced by chemotherapy:

The minimum dose is about 0.15 mg/kg doses, first dose is to be given before 15 min of chemotherapy and another doses are administered 4-8 hrs gap of after the first dose.

For Usual adult for nausea/vomiting:

The minimum dose is about 0.15 mg/kg doses, first dose is to be given 15 min before the chemotherapy and  another doses are administered 4-8hrs gap of after the first dose.

For Nausea /vomiting-radiation induced:

8mg to be taken orally for every 8hrs, give the first dose 1-2hrs prior to radiotherapy.

Oral: The minimum dosse is about 8mg to be taken for 3 times in a day.

For Pruritis:

The minimum dose is about 8mg to be taken intravenously before spinal anesthesia.

For Alcohol dependence:

The minimum dose is about 4mcg/kg two times a day.

Pediatric dose:

The dosage for children depends upon their age and weight.

Child weight below 40kg: The minimum is about o.1mg in a single dose IV administered over 2-5min,

Child weight about 40kg or above:The minimum dose is about 4mg single dose IV, administered over 2-5min.

It is mostly recommended to consult your doctor before giving any medication to the children.

Ondansetron side effects:

If the patient is experiencing any of the following side effects then consult your doctor immediately.

Severity: major

  • Headache
  • Weakness
  • Shortness of breathe
  • Fever
  • Confusion
  • Dizziness
  • Painful urination
  • Decreased urination
  • Lower back pain
  • Cough
  • Loss of appetite
  • Loss of consciousness
  • Nausea
  • Sweating
  • Noisy breathing

Severity: minor

  • Trouble sleeping
  • Restlessness
  • Irritability
  • Hyperventilation
  • Dry mouth
  • Shaking
  • Drooling
  • Loss of balance control
  • Twisting movements in the body

Ondansetron: brand names, price list

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