Methadone (Dolophine): Uses, Dosage & Side Effects

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(Last Updated On: September 6, 2017)

Methadone (Dolophine) belongs to the group of opioids and it is generally prescribed for the patients who are  addicted to heroin or other narcotic drugs. Opioids  are also called as Narcotics.

It is mainly used to treat severe pain to moderate pain. Hence, it is nothing but a pain reliever.

Information about Methadone:

Methadone may slow down or stop your breathing and it is also reported that this medicine becomes habit forming even when it is taken on regular basis as prescribed. Hence, it should not be taken for longer duration.

This medicine should be used as exactly how the doctor has prescribed and it is must for the patient to follow the directions written on the prescription label. It should not be used in small or large doses and also not for longer duration than prescribed. This medicine should be taken for only 4-8 weeks and if any extension is required then consult your doctor.

Do not crush or chew the tablets or capsules. Do not swallow the tablets or capsules rather consume it with a full glass of water.

Misuse of narcotic drugs may cause addiction, overdose, or even sometimes death, especially in the case of children and elderly patients. Do not consume alcohol while you are undergoing any kind of medication.

Dosage pattern of Methadone:

For Pain

For Adults: The minimum dosage is about 2.5-10 mg for every 8-12 hrs of time interval or as directed by the physician


Initial dose: The minimum dose is about 20-30 mg to be taken orally once in a day.

Maximum dose: It should not exceed 30 mg of dose.

Tablets: 2-4 mg to be taken orally for every 4-6 hrs of time interval or as directed by your doctor.

The above mentioned dosages are just reviewed by our web users, the dosage may vary from person to person. Hence, ask your doctor before intake of any medicines.

Increasing or decreasing the present dosage of a patient is to be done under medical observation. This increment of dosage requires only when patient’s pain severity increases or in the cases where the analgesic is to be given to the patient. Patients with the renal and hepatic impairment can start on a lower starting dose.

Methadone overdose:

The symptoms are life-threatening. Therefore, consult your doctor immediately if any of the following symptoms are seen or experienced.

Symptoms include:

  • Decreased awareness
  • Increased sensitivity
  • No muscle movement
  • Sleepiness
  • Unusual drowsiness

Methadone withdrawal symptoms:

Methadone side effects:

Severity: major

  • Convulsions
  • Blurred vision
  • Decreased urination
  • Dry mouth
  • Decreased urination
  • chest pain
  • rapid breathing
  • severe stomach pain
  • trouble breathing
  • vomiting
  • unusual tiredness
  • stiff neck
  • mental changes
  • irregular heartbeat

Severity: minor

  • nausea
  • difficulty in muscle movement
  • joint pains
  • difficulty in bowel movement
  • acidic stomach
  • back pain
  • indigestion
  • irritability
  • muscle spasm
  • stomach discomfort
  • being forgetful
  • bleeding
  • changes in speech
  • clumsiness

Methadone: brand names, price list


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